| Lowes MA, Bowcock AM, and Krueger JG. Pathogenesis and therapy of psoriasis. Nature 445:866-873. (2007). Abstract |
| Liu Y, Krueger JG, Bowcock AM. Psoriasis: genetic associations and immune system changes. Genes Immun. 2007 Jan;8(1):1-12. Epub 2006 Nov 9. Abstract |
| Gurnett CA, Bowcock AM, Dietz FR, Morcuende JA, Murray JC, and Dobbs MB: Two novel point mutations in the long-range SHH enhancer in three families with triphalangeal thumb and preaxial polydactyly. Am. J. Med. Genet. Part A, 143:27-32 (2007).Abstract |
| Gurnett CA, Dobbs MB, Keppel CR, Pincus ER, Jansen LA, and Bowcock AM. Additional evidence of a locus for complex febrile and afebrile seizures on chromosome 12q22-23.3 Neurogenetics 8:61-63 (2007).Abstract |
| Liu Y, Krueger J, and Bowcock AM. Psoriasis: Genetic associations and immune system changes. Gene & Immunity. In press (2006). |
| Gurnett CA, Dobbs MB, Nordsieck EJ, Keppel C, Goldfarb CA, Morcuende JA, and Bowcock AM. Evidence for an additional locus for split hand/foot malformation in chromosome region 8q21.11-q22.3. Am. J. Med. Genet A. 140(16):1744-8. (2006).Abstract |
| Gale SE, Frolov A, Han X, Bickel PE, Cao L, Bowcock A, Schaffer JE, Ory DS. A regulatory role for AGPAT2 in adipocyte differentiation. J. Biol Chem. 281:11082-11089 (2006). Abstract |
| Haider AS, Peters SB, Kaporis H, Cardinale I, Fei J, Ott J, Blumenberg M, Bowcock AM, Krueger JG, Carucci JA. Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia.J. Invest Dermatol. 126(4):869-881 (2006). Abstract |
| Dobbs MB, Gurnett CA, Pierce B, Exner GU, Robarge J, Morcuende JA, Cole WG, Templeton PA, Foster B, Bowcock AM. HOXD10 M319K mutation in a family with isolated congenital vertical talus. J. Orthop Res. 24(3):448-453 (2006). Abstract |
| Sun C, Mathur P, Dupuis J, Tizard R, Ticho B, Crowell T, Gardner H, Bowcock AM, Carulli J. Peptidoglycan recognition proteins Pglyrp3 and Pglyrp4 are encoded from the epidermal differentiation complex and are candidate genes for the Psors4 locus on chromosome 1q21. Hum. Genet. 119(1-2):113-125 (2006). Abstract |
| Morar N, Bowcock AM, Harper JI, Cookson WO, Moffatt MF. Investigation of the Chromosome 17q25 PSORS2 Locus in Atopic Dermatitis. J. Invest. Dermatol. 126(3):603-606 (2006). Abstract |
| Dobbs MB, Gurnett CA, Gordon RJ, Morcuende JA, Bowcock AM. Variable hand and foot abnormalities in family with congenital vertical talus and DCMP-1 gene mutation. J. Ortho. Res. 23:1490-1494 (2005). |
| Helms C, Pelsue S, Cao L, Lamb E, Loffredo B, Taillon-Miller P, Herrin B, Burzenski LM, Gott B, Lyons BL, Keppler D, Shultz LD, Bowcock AM. The Tetratricopeptide repeat domain 7 gene is mutated in flaky skin mice: a model for psoriasis, autoimmunity, and anemia. Exp. Biol. Med. 230:659-667 (2005). Abstract |
| Helms C, Saccone NL, Cao L, Wright-Daw, JA, Kai C, Hsu TM, Taillon-Miller P, Duan S, Gordon D, Pierce B, Ott J, Rice J, Fernandez-Vina MA, Kwok P-Y, Menter A, and Bowcock AM. Localization of PSORS1 to a haplotype block harboring HLA-C and distinct from corneodesmosin and HCR. Hum. Genet. 19:1-11 (2005). Abstract |
| Williams F, Meenagh A, Sleator C, Cook D, Fernandez-Vina M, Bowcock AM, and Middleton D. Activating killer cell immunoglobulin-like receptor gene KIR2DS1 is associated with psoriatic arthritis. Hum. Immunol. 66:836-841 (2005). Abstract |
| Bowcock AM and Krueger JG. Getting under the skin: The immunogenetics of psoriasis. Nat. Reviews/Immunology 5:699-711 (2005). Abstract |
| Bowcock AM. The genetics of psoriasis and autoimmunity. Annu. Rev. Genomics Hum. Genet. 6:93-121 (2005). Abstract |
| Bashiardes S, Veile R, Helms C, Mardis ER, Bowcock AM, and Lovett M. Direct genomic selection. Nat. Methods 2:63-69 (2005). Abstract |
| Krueger, JG and Bowcock AM. Psoriasis pathophysiology: Current concepts of pathogenesis. Ann. Rheum. Dis. 64:30-36 (2004). Abstract |
| Gordon D, Hayes C, Johnnidis C, Patel SB, Bowcock AM, and Ott J. A transmission disequilibrium test for general pedigrees that is robust to the presence of random genotyping errors and any number of untyped parents. Eur. J. Hum. Genet. 12:752-761 (2004). Abstract |
| Bowcock AM. Psoriasis genetics: the way forward. J. Invest. Dermatol. 122:xv-xvii (2004). Abstract |
| Lew W, Bowcock AM, and Krueger JG. Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and 'Type 1' inflammatory gene expression. TRENDS Immunol. 25:295-305 (2004). Abstract |
| Bashiardes S, Veile R, Allen M, Wise C, Dobbs MB, Morcuende JA, Szappanos L, Herring JA, Bowcock AM and Lovett M. SNTG1, the gene encoding gamma1-syntrophin: A candidate gene for idopathic scoliosis. Hum. Genet. 115:81-89 (2004). Abstract |
| Suomela S, Cao L, Bowcock A and Saarialho-Kere U. Interferon alpha-inducible protein 27 (IFI27) is up-regulated in psoriatic skin and certain epithelial cancers. J. Invest. Dermatol. 122:717-721 (2004). Abstract |
| Capon F, Helms C, Veal CD, Tillman D, Burden AD, Barker JN, Bowcock AM and Trembath RC. Genetic analysis of PSORS2 markers in a UK dataset supports the association between RAPTOR SNPs and familial psoriasis. J. Med. Genet. 41:459-460 (2004). Abstract |
| Bowcock AM, and Cookson WO. The genetics of psoriasis, psoriatic arthritis and atopic dermatitis. Hum. Molec. Genet. 13:R43-R55 (2004). Abstract |
| Helms C, Cao L, Krueger JG, Wijsman EM, Chamian F, Gordon D, Heffernan M, Daw JA, Robarge J, Ott J, Kwok P-Y, Menter A and Bowcock AM. A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis. Nat. Genet. 35:349-356 (2003). Abstract |
| Bowcock AM, and Barker JN. Genetics of psoriasis: The potential impact on new therapies. J. Am. Acad. Derm. 49:S51-52 (2003). Abstract |
| Allen M, Barker JWN, Bowcock AM, Burden AD, Chia N, Capon F, Christophers E, Daly MJ, Elder JT, Helms C, Henseler T, Jenisch S, Menter A, Mistry R, Nair RP, Stuart PE, Tillman D, Trembath RC, Veal C, and Voorhees JJ. The international psoriasis genetics study: Assessing linkage to 14 candidate susceptibility loci in a 942 affected-sib-pair cohort. Am. J. Hum. Genet. 73:430-437 (2003). Abstract |
| Haque WA, Oral EA, Dietz K, Bowcock AM, Agarwal AK, and Garg A. Risk factors for diabetes in familial partial lipodystrophy, Dunnigan variety. Diabetes Care 26:1350-1355 (2003). Abstract |
| Zhou X, Krueger JG, Kao M-C, Lee E, Du F, Menter A, Wong WH, and Bowcock AM. Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array. Physiol. Genomics 13:69-78 (2003). Abstract |
| Speckman RA, Daw JA, Helms C, Duan S, Cao L, Taillon-Miller P, Kwok P-Y, Menter A, and Bowcock AM. Novel immunoglobulin superfamily gene cluster, mapping to a region of human chromosome 17q25.1, linked to psoriasis susceptibility. Hum. Genet. 112:34-41 (2002). Abstract |
| Garg A, Speckman RA, and Bowcock AM. Multisystem dystrophy syndrome due to novel missense mutations in the amino-terminal head and alpha-helical rod domains of the lamin A/C gene. Am. J. Med. 112:549-555 (2002). Abstract |
| Agarwal AK, Arioglu E, de Almeida S, Akkoc N, Taylor SI, Bowcock AM, Barnes RI, and Garg A. AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34. Nat. Genet. 31:21-23 (2002). Abstract |
| Du F, Mahadevappa M, Warrington JA, and Bowcock, AM. Gene expression changes in endometrial cancer. In "Microarrays and Cancer", Eds. Warrington JA, Wong D, and Todd R. Eaton Publishing, pp 113-125 (2002). |
| Bowcock AM, Shannon W, Du F, Duncan J, Kai C, Aftergut K, Catier J, Fernandez-Vina M, and Menter A. Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies. Hum. Mol. Genet. 10:1793-1805 (2001). Abstract |
| Bowcock AM, and Lovett M. Zeroing in on tolerance. Nat. Med. 7:279-281 (2001). Abstract |
| Swoboda, KJ, Soong BW, McKenna C, Brunt ER, Litt M, Bale JF Jr, Ashizawa T, Bennett LB, Bowcock AM, Roach ES, Gerson D, Matsuura T, Heydemann PT, Nespeca MP, Jankovic J, Leppert M, and Ptacek LJ. Paroxysmal kinesigenic dyskinesia and infantile convulsions. Clinical and linkage studies. 2000. Neurology 57:S42-S48 (2001). |
| Xu, XL, Wu LC, Du F, Davis A, Peyton M, Tomizawa Y, Maitra A, Tomlinson G, Gazdar AF, Weissman BE, Bowcock AM, Baer R, and Minna JD. Inactivation of human SRBC, located within the 11p15.5-p15.4 tumor suppressor region, in breast and lung cancers. Cancer Res. 61:7943-7949 (2001). Abstract |
| Garg, A, Vinaitheerthan M, Weatherall PT, and Bowcock AM. Phenotypic heterogeneity in patients with familial partial lipodystrophy (Dunnigan variety) related to the site of mis-sense mutations in Lamin A/C (LMNA) gene. J. Clin. Endocrin. & Metabolism, 86:59-65 (2001). Abstract |
| Swoboda, KJ, Soong BW, McKenna C, Brunt ER, Litt M, Bale JF, Ashizawa T, Bennett LB, Bowcock AM, Roach ES, Gerson D, Matsuura T, Heydemann PT, Nespeca MP, Jankovic J, Leppert M, and Ptacek LJ. Paroxysmal kinesigenic dyskinesia and infantile convulsions: Clinical and linkage studies. Neurology 55:224-230 (2000). Abstract |
| Chatila TA, Blaeser F, Ho N, Lederman HM, Voulgaropoulos C, Helms C, and Bowcock AM. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J. Clin. Invest. 106:R75-R81 (2000). Abstract |
| Wise CA, Bennett LB, Pascual V, Gillum JD, Bowcock AM. Localization of a gene for familial recurrent arthritis. Arthritis & Rheum. 43:2041-2045 (2000). Abstract |
| Wise CA, Barnes RB, Gillum J, Herring JA, Bowcock AM, and Lovett M. Localization of susceptibility to familial idiopathic scoliosis. Spine 25:2372-2380 (2000). Abstract |
| Speckman, RA, Garg A, Du F, Bennett L, Veile R, Arioglu E, Shmidt HH-J, Taylor SI, Lovett M, and Bowcock AM. Mutational and haplotype analyses in familes with familial partial lipodystrophy (Dunnigan variety) reveal recurrent mis-sense mutations in the globular C-terminal domain of Lamin A/C. Am. J. Hum. Genet. 66:1192-1198 (2000). Abstract |
| Zhivotovsky, LA, Bennett L, Bowcock AM, and Feldman MW. Human population expansion and microsatellite variation. Mol. Biol. & Evol. 17:757-767 (2000). Abstract |
| Bennett, LB, Roach ES, and Bowcock AM. A locus for paroxysmal kinesigenic dyskinesia maps to human chromosome 16. Neurology 54:125-130 (2000). Abstract |